Cysteamine rapidly decreases mitotic cells in random culture of Hela S-3 cells. | Zendy

Yoshinari Takagi | Zendy; Mikio Shikita | Zendy

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Cysteamine rapidly decreases mitotic cells in random culture of Hela S-3 cells.

Author(s) -

Yoshinari Takagi,

Mikio Shikita

Publication year - 1983

Publication title -

journal of radiation research

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.643

H-Index - 60

eISSN - 1349-9157

pISSN - 0449-3060

DOI - 10.1269/jrr.24.285

Subject(s) - cysteamine , mitosis , hela , chemistry , microbiology and biotechnology , cell culture , cytolysis , cell , biology , biochemistry , cytotoxicity , genetics , in vitro

Mitotic cells disappeared nearly completely within 60 min after the addition of 30 mM cysteamine in HeLa S-3 cell culture, while the control culture contained mitotic cells with the frequency of 3.4%. Inhibition of mitosis became gradually irreversible when the treatment was extended over 60 min, but cytolysis occurred much more slowly. Ethanolamine exhibited a similar but much less significant effect.

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