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滋 賀医 科 大 学,放 射 線 基 礎 医 学 教 室*,滋賀医科大学,RIセ ンタ ー**,滋 賀 県 大 津 市 瀬 田月 輪 町 〒520-21 WR-2721/Ehrlich's Ascites Tumor/Growth Suppression Mice were injected daily with a radioprotector WR-2721 after inoculation with Ehrlich's ascites tumor cells. Increases in weight of mice, volume of ascitic fluid and number of ascitic cells per mouse were reduced by the daily administration of 5 mg/mouse of the drug, indicating a suppyessive effect of WR-2721 on growth of ascitic cells. But daily treatment with 5 mg/ mouse of WR-2721 caused earlier death of tumor-bearing mice.

journal of radiation research

Effects of daily treatment with a radioprotector WR-2721 on Ehrlich's ascites tumors in mice: Suppression of tumor cell growth and earlier death of tumor-bearing mice.