Effects of daily treatment with a radioprotector WR-2721 on Ehrlich's ascites tumors in mice: Suppression of tumor cell growth and earlier death of tumor-bearing mice. | Zendy

M. Ikebuchi | Zendy; S Shinohara | Zendy; Hiromi Kimura | Zendy; Katsuhiko Morimoto | Zendy; Azusa Shima | Zendy; Takashi Aoyama | Zendy

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Effects of daily treatment with a radioprotector WR-2721 on Ehrlich's ascites tumors in mice: Suppression of tumor cell growth and earlier death of tumor-bearing mice.

Author(s) -

M. Ikebuchi,

S Shinohara,

Hiromi Kimura,

Katsuhiko Morimoto,

Azusa Shima,

Takashi Aoyama

Publication year - 1981

Publication title -

journal of radiation research

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.643

H-Index - 60

eISSN - 1349-9157

pISSN - 0449-3060

DOI - 10.1269/jrr.22.258

Subject(s) - ascites , ehrlich ascites , ascitic fluid , neoplasm , pharmacology , ratón , tumor cells , drug , medicine , cancer research , biology , immunology , pathology

滋賀医科大学,放射線基礎医学教室*,滋賀医科大学,RIセンター**,滋賀県大津市瀬田月輪町〒520-21 WR-2721/Ehrlich's Ascites Tumor/Growth Suppression Mice were injected daily with a radioprotector WR-2721 after inoculation with Ehrlich's ascites tumor cells. Increases in weight of mice, volume of ascitic fluid and number of ascitic cells per mouse were reduced by the daily administration of 5 mg/mouse of the drug, indicating a suppyessive effect of WR-2721 on growth of ascitic cells. But daily treatment with 5 mg/ mouse of WR-2721 caused earlier death of tumor-bearing mice.

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