English (United Kingdom)

https://curated-unify.zendy.io/wp-json/zendy-region/v1/featured_content/oa?rat=en

https://curated-unify.zendy.io/wp-json/zendy-region/v1/highlighted_journal/

Global: Zendy Plus annual

Presents the access of premium content as premium feature

Premium Content

Presents the keyphrase highlighting as premium feature

Keyphrase Highlighting

Presents the summarisation as premium feature

Summarisation

Insights

Presents the pdf analysis as premium feature

PDF Analysis

Presents the zaia usage as premium feature

ZAIA

Global: Zendy Tools annual

Global: Zendy Free Plan

Global: Zendy Tools monthly

Global: Zendy Plus monthly

大竹正徳:広 島大学理学部動物学教室,広 島市東千 田町,〒730 Various statistical models designed to determine the effects of radiation dose on mortality of atomic bomb survivors in Hiroshima and Nagasaki from specific cancers were evaluated on the basis of a basic k(age) •~ c(dose) •~ 2 contingency table. From the aspects of application and fits of different models, analysis based on the additive logit model was applied to the mortality experience of this population during a 22 year period from 1 October 1950 to 31 December 1972. The advantages and disadvantages of the additive logit model were demon strated. Leukemia mortality showed a sharp rise with increase in dose. In particular, the dose response relationship suggests a possible curvature as the log linear of the dose estimated to be more than 600 rad was set arbitrarily at 600 rad and then the average dose in the 200+ rad group would change from 434 to 350 rad. In the 22 year period from 1950 to 1972, a high mortality risk due to radiation was observed in survivors with doses of 200 rad and over for all cancers except leukemia, cancer of the gastrointestinal tract, lung cancer, cancer of respira tory system and other cancers. On the other hand, during the latest period from 10,65 to 1972 a significant risk was noted also for stomach and breast cancers. Survivors who were nine or less in age at the time of the bomb (ATB) and were exposed to high doses of 200+ rad appeared to show a high mortality risk due to all cancers except leukemia, although the num ber of observed deaths is yet small. A number of interesting areas are discussed from the statistical and epidemiological stand points, i. e., the numerical comparison of risks in various models, the general evaluation of cancer mortality by the additive logit model, the dose response relationship, the relative risk in the high dose group, the time period of radiation induced cancer mortality, the difference of dose response between Hiroshima and Nagasaki and the relative biological effectiveness (RBE) of neutrons.

journal of radiation research

Radiation Effects on Cancer Mortality Among A-Bomb Survivors, 1950-72: Comparison of Some Statistical Models and Analysis Based on the Additive Logit Model