Chemical Radiation Protection in Man as Revealed by Chromosome Aberrations in Peripheral Lymphocytes
Author(s) -
Yoshimasa Tanaka,
Tsutomu Sugahara
Publication year - 1970
Publication title -
journal of radiation research
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.643
H-Index - 60
eISSN - 1349-9157
pISSN - 0449-3060
DOI - 10.1269/jrr.11.166
Subject(s) - peripheral , radiation therapy , incidence (geometry) , chromosome , medicine , nasopharyngeal carcinoma , cervical carcinoma , oncology , cancer research , pathology , biology , genetics , cancer , cervical cancer , physics , optics , gene
Patients with cervical carcinoma under radiotherapy have been followed during and after radiotherapy for the incidence of chromosome aberrations in peripheral lymphocytes. In patients treated with adrenochrome monoguanylhydrazone methansulfonate (100 mg) before every irradiation the incidence was significantly lower than in those without the treatment. The result indicates chemical protection in man for the first time.
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