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Effect of Dose Fractionation on Pulmonary Complications during Total Body Irradiation
Author(s) -
Hiromi Izawa,
Hisako Hirowatari,
Yuriko Yahata,
Yasuharu Hamano,
Kana Ito,
Anneyuko I. Saito,
Hideo Yamamoto,
Kouhei Miura,
Kumiko Karasawa,
Keisuke Sasai
Publication year - 2011
Publication title -
journal of radiation research
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.643
H-Index - 60
eISSN - 1349-9157
pISSN - 0449-3060
DOI - 10.1269/jrr.10173
Subject(s) - medicine , total body irradiation , fractionation , pneumonitis , regimen , lung , dose fractionation , incidence (geometry) , radiation therapy , chemotherapy , chemistry , physics , organic chemistry , optics , cyclophosphamide
Total body irradiation (TBI) is an important component of conditioning regimens for Allogeneic bone marrow transplantation (BMT). Interstitial pneumonitis (IP) and other pulmonary disorders are known regimen-related complications. The incidence of IP is related to the dose rate and dose fractionation; however, there is a paucity of clinical data regarding the optimal dose fractionation. This retro...

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