Protective Effects of Vitamin Glycosides on γ-radiation and H2O2-Induced Decomposition of Thymine in Aqueous Solutions | Zendy

О. И. Шадыро | Zendy; P. Yu. Lagutin | Zendy; Irina Edimecheva | Zendy; С. Д. Бринкевич | Zendy; Tsutomu Kagiya | Zendy

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Protective Effects of Vitamin Glycosides on γ-radiation and H2O2-Induced Decomposition of Thymine in Aqueous Solutions

Author(s) -

О. И. Шадыро,

P. Yu. Lagutin,

Irina Edimecheva,

С. Д. Бринкевич,

Tsutomu Kagiya

Publication year - 2008

Publication title -

journal of radiation research

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.643

H-Index - 60

eISSN - 1349-9157

pISSN - 0449-3060

DOI - 10.1269/jrr.08004

Subject(s) - ascorbic acid , chemistry , thymine , radical , aqueous solution , decomposition , vitamin c , glycoside , adduct , photochemistry , vitamin , organic chemistry , medicinal chemistry , biochemistry , dna , food science

Effects of ascorbic acid (AA), ascorbic acid glycoside (AAG) and alpha-tocopherol monoglycoside (TMG) on radiation - and H(2)O(2)-induced decomposition of thymine in aqueous solutions were investigated. Of the three compounds studied, AAG was found to possess the most marked protector properties. An explanation of this phenomenon has been given in terms of differences in molecular structures of AA and AAG, as well as properties of radical adducts formed during their interaction with OH radicals.

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