Th17 response was elevated in the patients with chronic lymphocytic leukemia: a one year follow-up | Zendy

Dijiao Tang | Zendy; Qian Niu | Zendy; Nenggang Jiang | Zendy; Jingjing Li | Zendy; Qin Zheng | Zendy; Yongqian Jia | Zendy

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Th17 response was elevated in the patients with chronic lymphocytic leukemia: a one year follow-up

Author(s) -

Dijiao Tang,

Qian Niu,

Nenggang Jiang,

Jingjing Li,

Qin Zheng,

Yongqian Jia

Publication year - 1969

Publication title -

pakistan journal of medical sciences

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.316

H-Index - 30

eISSN - 1682-024X

pISSN - 1681-715X

DOI - 10.12669/pjms.305.5252

Subject(s) - medicine , foxp3 , chronic lymphocytic leukemia , flow cytometry , immune system , treg cell , leukemia , cd8 , immunology , il 2 receptor , gastroenterology , oncology , t cell

Objective : In this study, we aimed to investigate changes of peripheral Th17 and Treg cells frequencies in the newly-diagnosed Chronic Lymphocytic Leukemia (CLL) patients for 12 months. Methods : In this research, 50 CLL patients were enrolled. Circulating Th1, Th17 cells and CD4+CD25+Foxp3+Treg cells were analyzed by flow cytometry. Plasma levels of related cytokines were detected by enzyme-linked immuno sorbent assay (ELISA). The study was carried out from January 2012 to October 2013 at Department of Laboratory Medicine, West China Hospital, Sichuan University, Chengdu, P.R. China.

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