Atypical cause of a typical chest pain

A 56 year old African American female who had a past medical history of transient ischemic attack in 2006 presented in our emergency department with first episode of sudden onset of severe central chest pain radiating to both arms , exaggerated by exertion, without any relieving factors, associated with nausea and sweating. She was taking baby aspirin, folic acid and multivitamin regularly. She did not have any history of smoking, alcohol or drug abuse. On Examination, she was in moderate distress due to pain, her pulse rate was 110 per minute (regular), and blood pressure was 153/85 mm HG. She was having mild tenderness in left upper quadrant. Rest of the physical examination was benign. Her initial electrocardiogram (EKG) did not show any acute ST segment or T wave changes. Troponin-I was also negative. She was started on oxygen, intra venous morphine and normal saline and shifted to the medical floor for further management. Her serial EKG’s and troponin’s remain negative. Transthoracic echocardiogram did not show any evidence of wall motion abnormalities. Further laboratory data showed that she was having hemolytic anemia with hemoglobin of 9.7 gm/dl and reticulocyte count of 4.8%. Upon further digging into the history, she mentioned that she had been periodically visiting hematology clinic, although she did not remember the reason for that. Once we contacted the