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Post-hysterectomy vaginal cuff cancer secondary to HPV infection and CIN
Author(s) -
Xiaoxia Liu,
Ying Yue,
Shan Zong
Publication year - 2013
Publication title -
pakistan journal of medical sciences
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.316
H-Index - 30
eISSN - 1682-024X
pISSN - 1681-715X
DOI - 10.12669/pjms.294.3073
Subject(s) - medicine , hysterectomy , cervical intraepithelial neoplasia , vaginal cancer , hpv infection , cervical cancer , endometrial cancer , gynecology , cancer , human papilloma virus , obstetrics , surgery
We present a case report of secondary vaginal cancer after complete hysterectomy due to myoma that was complicated by low-grade cervical intraepithelial neoplasia (CIN I) and human papilloma virus (HPV) infection. After complete hysterectomy, the HPV DNA level in the vaginal tissue was obviously increased, and vaginal cancer was diagnosed 6 months later. We conclude that HPV infection can cause vaginal cancer after complete hysterectomy in cases complicated by CIN. Therefore, HPV should be regularly assessed during the postoperative follow-up period.

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