Open AccessTrading translation with RNA-binding proteins
Author(s) -
Irina Abaza,
Fátima Gebauer
Publication year - 2008
Publication title -
rna
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.037
H-Index - 171
eISSN - 1469-9001
pISSN - 1355-8382
DOI - 10.1261/rna.848208
Subject(s) - biology , rna binding protein , translation (biology) , rna , rna splicing , post transcriptional modification , messenger rna , computational biology , riboswitch , rna editing , microbiology and biotechnology , genetics , non coding rna , gene
RNA-binding proteins regulate every aspect of RNA metabolism, including pre-mRNA splicing, mRNA trafficking, stability, and translation. This review summarizes the available information on molecular mechanisms of translational repression by RNA-binding proteins. By using a specific set of well-defined examples, we also describe how regulation can be reversed.
Accelerating Research
Robert Robinson Avenue,
Oxford Science Park, Oxford
OX4 4GP, United Kingdom
Address
John Eccles HouseRobert Robinson Avenue,
Oxford Science Park, Oxford
OX4 4GP, United Kingdom