The effect of nonsense codons on splicing: A genomic analysis: FIGURE 1. | Zendy

Xiang Zhang | Zendy; James Lee | Zendy; Lawrence A. Chasin | Zendy

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The effect of nonsense codons on splicing: A genomic analysis: FIGURE 1.

Author(s) -

Xiang Zhang,

James Lee,

Lawrence A. Chasin

Publication year - 2003

Publication title -

rna

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 3.037

H-Index - 171

eISSN - 1469-9001

pISSN - 1355-8382

DOI - 10.1261/rna.5060403

Subject(s) - biology , nonsense , rna splicing , genetics , computational biology , alternative splicing , evolutionary biology , gene , exon , rna

The phenomenon of nonsense-associated altered splicing raises the possibility that the recognition of in-frame nonsense codons is used generally for exon identification during pre-mRNA splicing. However, nonsense codon frequencies in pseudo exons and in regions flanking 5' splice sites are no greater than that expected by chance, arguing against the widespread use of this strategy as a means of rejecting potential splice sites.

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