After the ribosome structure: How does translocation work?: FIGURE 1.
Author(s) -
Simpson Joseph
Publication year - 2003
Publication title -
rna
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.037
H-Index - 171
eISSN - 1469-9001
pISSN - 1355-8382
DOI - 10.1261/rna.2163103
Subject(s) - biology , ribosome , chromosomal translocation , ribosomal rna , computational biology , transfer rna , protein biosynthesis , translation (biology) , ribosomal protein , messenger rna , eukaryotic ribosome , genetics , microbiology and biotechnology , rna , gene
Structures of the ribosomal large and small subunits have been solved to atomic resolution by X-ray crystallography. These structures provide a new foundation to address the complex process of protein biosynthesis by the ribosome. Translocation of the tRNA–mRNA complex is one of the most fascinating tasks performed by the ribosome. The impact of the crystal structures in understanding the molecular mechanism of translocation is highlighted in this review.
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