Open AccessBreeding nude (nu/nu) mice
Author(s) -
C. M. Hetherington,
Moira A. Hegan
Publication year - 1975
Publication title -
laboratory animals
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.62
H-Index - 63
eISSN - 1758-1117
pISSN - 0023-6772
DOI - 10.1258/002367775780994907
Subject(s) - offspring , weaning , biology , zoology , andrology , genetics , medicine , pregnancy
By using as sires homozygous nude males bearing thymus glands from their normal siblings, heterozygous females yield 50% nu/nu offspring under conventional conditions. Most nu/nu females are fertile, but in our experience only 20% of them rear nude litters to weaning age.
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