Open AccessSupersensitivity of Amylase Secretion from Rat Parotid Tissue—Its Selective Nature for the β2-Adrenergic Response
Author(s) -
Fumiaki Hata,
Yutaka Noguchi,
Yasuko Ishikawa,
Naohiko Koda,
Hideyuki Ishida
Publication year - 1985
Publication title -
japanese journal of pharmacology/japanese journal of pharmacology
Language(s) - English
Resource type - Journals
eISSN - 1347-3506
pISSN - 0021-5198
DOI - 10.1254/jjp.37.129
Subject(s) - secretion , endocrinology , amylase , medicine , beta (programming language) , agonist , chemistry , parotid gland , adrenergic , enzyme , receptor , biochemistry , pathology , computer science , programming language
In rat parotid tissue, amylase secretion and accumulation of cyclic AMP were not selective responses to the different beta-subtypes, beta 1 and beta 2. However, the supersensitivity of the amylase secretory response induced by brief pretreatment with beta-agonist was due specifically to a beta 2-adrenergic response.