Open AccessAlterations in Osteopontin Modify Muscle Size in Females in Both Humans and Mice
Author(s) -
Eric P. Hoffman,
Heather GordishDressman,
Virginia D. McLane,
Joseph M. Devaney,
Paul D. Thompson,
Paul S. Visich,
Paul M. Gordon,
Linda S. Pescatello,
Robert F. Zoeller,
Niall M. Moyna,
Theodore J. Angelopoulos,
Elena Pegoraro,
Gregory A. Cox,
Priscilla M. Clarkson
Publication year - 2013
Publication title -
medicine and science in sports and exercise
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.703
H-Index - 224
eISSN - 1530-0315
pISSN - 0195-9131
DOI - 10.1249/mss.0b013e31828093c1
Subject(s) - osteopontin , medicine , endocrinology , biology , eccentric , cohort , skeletal muscle , creatine kinase , muscle hypertrophy , physics , quantum mechanics
An osteopontin (OPN; SPP1) gene promoter polymorphism modifies disease severity in Duchenne muscular dystrophy, and we hypothesized that it might also modify muscle phenotypes in healthy volunteers.