Open AccessMuscle Protein Synthesis Response to Exercise Training in Obese, Older Men and Women
Author(s) -
Gordon I. Smith,
Dennis T. Villareal,
David R. Sinacore,
Krupa Shah,
Bettina Mittendorfer
Publication year - 2012
Publication title -
medicine and science in sports and exercise
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.703
H-Index - 224
eISSN - 1530-0315
pISSN - 0195-9131
DOI - 10.1249/mss.0b013e3182496a41
Subject(s) - anabolism , medicine , basal (medicine) , endocrinology , meal , muscle protein , skeletal muscle , biology , insulin
Physical activity and eating are two major physiological muscle growth stimuli. Although muscle protein turnover rates are not different in young and middle-aged men and women, we recently found that the basal rate of muscle protein synthesis is greater and the anabolic response to mixed-meal intake is blunted in 65- to 80-yr-old women compared with men of the same age. Whether older women are also resistant to the anabolic effect of exercise is not known.