Open AccessPostexercise Skeletal Muscle Glucose Transport Is Normal in Kininogen-Deficient Rats
Author(s) -
George G. Schweitzer,
Gregory D. Cartee
Publication year - 2011
Publication title -
medicine and science in sports and exercise
Language(s) - English
Resource type - Journals
eISSN - 1530-0315
pISSN - 0195-9131
DOI - 10.1249/mss.0b013e31820a7f65
Subject(s) - medicine , endocrinology , kininogen , insulin , glycogen , skeletal muscle , kallikrein , chemistry , bradykinin , biology , enzyme , biochemistry , receptor
A single exercise bout stimulates skeletal muscle glucose transport (GT) in the absence or presence of insulin. It has been suggested that the kallikrein-kinin system may contribute to exercise effects on both insulin-independent and insulin-dependent GT. Plasma kininogen, a key kallikrein-kinin system component, is a protein substrate for the enzyme kallikrein and the source of the peptide bradykinin.