Open AccessEffects of Aerobic Exercise on Lipid-Effector Molecules of the Innate Immune Response
Author(s) -
Jacqueline L. Kiwata,
Rabin Anouseyan,
Robert A. Desharnais,
Andrew Cornwell,
Nazareth Khodiguian,
Edith Porter
Publication year - 2014
Publication title -
medicine and science in sports and exercise
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.703
H-Index - 224
eISSN - 1530-0315
pISSN - 0195-9131
DOI - 10.1249/mss.0000000000000137
Subject(s) - lysozyme , medicine , endocrinology , albumin , aerobic exercise , chemistry , immunology , respiratory tract , immune system , effector , respiratory system , biochemistry
Consistent, moderate-to-vigorous-intensity exercise has been associated with a lower risk of upper respiratory tract infection (URI). However, the molecular basis for this apparent protection has not yet been fully resolved. Host-derived lipids such as cholesteryl esters (CE) have emerged as important effector molecules of innate defense against infections. Here, we compared antimicrobial CE in nasal fluid before and after moderate-to-vigorous exercise between active and inactive subjects.