Open AccessFacile Synthesis of β,β-Difluorostyrenes via the Negishi Coupling of Thermally Stable 2,2-Difluorovinyl Zinc–TMEDA Complex
Author(s) -
Takeshi Fujita,
Tomohiro Ichitsuka,
Kohei Fuchibe,
Junji Ichikawa
Publication year - 2011
Publication title -
chemistry letters
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.492
H-Index - 114
eISSN - 1348-0715
pISSN - 0366-7022
DOI - 10.1246/cl.2011.986
Subject(s) - chemistry , negishi coupling , zinc , coupling (piping) , combinatorial chemistry , polymer chemistry , organic chemistry , metallurgy , catalysis , materials science
2,2-Difluorovinylzinc chloride–TMEDA complex, readily prepared from 1,1-difluoroethylene, undergoes the palladium-catalyzed coupling reaction with aryl halides to afford β,β-difluorostyrenes in hig...
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