Effects of Anoxia on Energy Metabolism in Crucian Carp Brain Slices Studied With Microcalorimetry | Zendy

Dan Johansson | Zendy; Göran Nilsson | Zendy; Erik Törnblom | Zendy

AI Assistant Blog Pricing

Home ZAIA Blog

Open Access

Effects of Anoxia on Energy Metabolism in Crucian Carp Brain Slices Studied With Microcalorimetry

Author(s) -

Dan Johansson,

Göran Nilsson,

Erik Törnblom

Publication year - 1995

Publication title -

journal of experimental biology

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.367

H-Index - 185

eISSN - 1477-9145

pISSN - 0022-0949

DOI - 10.1242/jeb.198.3.853

Subject(s) - crucian carp , energy charge , adenylate kinase , glycolysis , isothermal microcalorimetry , carp , biology , hypoxia (environmental) , carassius auratus , metabolism , biochemistry , energy metabolism , chemistry , biophysics , endocrinology , oxygen , fishery , fish <actinopterygii> , enzyme , physics , organic chemistry , quantum mechanics , enthalpy

Crucian carp (Carassius carassius L.) is an exceptionally anoxia-tolerant vertebrate. To determine whether isolated crucian carp brain tissue survives anoxia and whether it displays anoxic metabolic depression, heat production (using microcalorimetry), lactate production, ethanol production and the maintenance of ATP, ADP and AMP levels and energy charge were measured in telencephalic brain slices during anoxia. In response to anoxia, heat output decreased by 37 %, corresponding to a 31 % fall in ATP turnover rate. Adenylate phosphates and energy charge were well maintained and no ethanol was produced during anoxia. It is concluded that crucian carp brain tissue has an intrinsic capacity to tolerate anoxia and that it responds to anoxia by depressing metabolic rate and elevating the glycolytic rate, thereby maintaining ATP levels.

The content you want is available to Zendy users.

Already have an account? Click here to sign in.

Having issues? You can contact us here

Accelerating Research