The absence of an arterial pressure effect on filtration by perfused glomeruli of the hagfish, Eptatretus stouti (Lockington) | Zendy

J. A. Riegel | Zendy

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The absence of an arterial pressure effect on filtration by perfused glomeruli of the hagfish, Eptatretus stouti (Lockington)

Author(s) -

J. A. Riegel

Publication year - 1986

Publication title -

journal of experimental biology

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.367

H-Index - 185

eISSN - 1477-9145

pISSN - 0022-0949

DOI - 10.1242/jeb.126.1.361

Subject(s) - hagfish , glomerulus , oncotic pressure , perfusion , ficoll , medicine , renal function , chemistry , osmotic pressure , anatomy , endocrinology , kidney , biology , biochemistry , in vitro , peripheral blood mononuclear cell , albumin , vertebrate , gene

Single renal corpuscles of hagfish were perfused with a Ringer solution containing Ficoll 70 to simulate the colloid osmotic pressure of hagfish plasma. Simultaneous measurements were made of single glomerulus filtration rate (SGFR), perfusion pressure and the pressure in a vessel of the renal vasculature. The results confirm that SGFR is independent of pressure in the glomerular capillaries (PGC). The results also suggest that flow through glomeruli and SGFR are closely linked. Studies of the pressures in glomerular capillaries during periods when the perfusion rate was varied indicate that PGC reflects the area of the active capillaries and the rate of perfusion. Therefore, in the hagfish, PGC appears to be an effect of factors that cause glomerular filtration, not the main cause of that process.

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