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Retardation of Growth in Axolotls Resulting From Parathyroid Extract Administration
Author(s) -
J. H. Thompson,
Julian Huxley
Publication year - 1934
Publication title -
journal of experimental biology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.367
H-Index - 185
eISSN - 1477-9145
pISSN - 0022-0949
DOI - 10.1242/jeb.11.3.273
Subject(s) - parathyroid hormone , endocrinology , medicine , growth hormone , growth retardation , biology , hormone , calcium , pregnancy , genetics
Axolotls have been used in a series of experiments designed to test the growth-retarding properties of the parathyroid glands of mammals, prepared so as to include the anti-growth hormone. Such retardation of growth has been obtained, and is proportional to dosage. This extends the growth-retarding effect of this hormone to the Anamnia, and to forms which presumably have no parathyroid themselves. A lightening of colour in normally dark pigmented individuals was noted after a considerable period (about eight weeks) of treatment.

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