Clathrin-mediated endocytosis in budding yeast at a glance | Zendy

Rebecca Lu | Zendy; David G. Drubin | Zendy; Yidi Sun | Zendy

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Clathrin-mediated endocytosis in budding yeast at a glance

Author(s) -

Rebecca Lu,

David G. Drubin,

Yidi Sun

Publication year - 2016

Publication title -

journal of cell science

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.384

H-Index - 278

eISSN - 1477-9137

pISSN - 0021-9533

DOI - 10.1242/jcs.182303

Subject(s) - biology , budding yeast , endocytosis , clathrin , budding , yeast , microbiology and biotechnology , saccharomyces cerevisiae , genetics , cell

Clathrin-mediated endocytosis is an essential cellular process that involves the concerted assembly and disassembly of many different proteins at the plasma membrane. In yeast, live-cell imaging has shown that the spatiotemporal dynamics of these proteins is highly stereotypical. Recent work has focused on determining how the timing and functions of endocytic proteins are regulated. In this Cell Science at a Glance article and accompanying poster, we review our current knowledge of the timeline of endocytic site maturation and discuss recent works focusing on how phosphorylation, ubiquitylation and lipids regulate various aspects of the process.

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