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We report here that two distinct centriole lineages exist in Drosophila: somatic centrioles usually composed by microtubule doublets and germ line centrioles characterized by triplets. Remarkably, the transition from doublets to triplets in the testis occurs within the stem cell niche with the formation of the C-tubule. We demonstrated that the old mother centriole that stays in the apical cytoplasm of the male germline stem cells (GSCs) is invariably composed by triplets, whereas its daughter is always built by mixed doublets and triplets. This difference represents the first documentation of a structural asymmetry between mother and daughter centrioles in Drosophila GSCs and may reflect a correlation between the architecture of parent centrioles and their ability to recruit centrosomal proteins. We also found that the old mother centriole is linked to the cell membrane by distinct projections that may play an important role in keeping its apical position during centrosome separation.

The Drosophila centriole: conversion of doublets to triplets within the stem cell niche