Mouse pluripotent stem cells at a glance
Author(s) -
Siim Pauklin,
Roger A. Pedersen,
Ludovic Vallier
Publication year - 2011
Publication title -
journal of cell science
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.384
H-Index - 278
eISSN - 1477-9137
pISSN - 0021-9533
DOI - 10.1242/jcs.074120
Subject(s) - epiblast , biology , embryonic stem cell , embryoid body , germ layer , stem cell , induced pluripotent stem cell , microbiology and biotechnology , blastocyst , inner cell mass , endoderm , ectoderm , reprogramming , genetics , gastrulation , embryo , cell , embryogenesis , gene
Embryonic stem cells (ESCs) are derived from the inner cell mass (ICM) of an embryo at the blastocyst stage. They are characterised by the ability to proliferate indefinitely (or self-renew) in vitro while maintaining pluripotency, i. e. the capacity to differentiate into germ cells and a broad
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