Open AccessThe haematopoietic stem cell niche at a glance
Author(s) -
Cristina Lo Celso,
David T. Scadden
Publication year - 2011
Publication title -
journal of cell science
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.384
H-Index - 278
eISSN - 1477-9137
pISSN - 0021-9533
DOI - 10.1242/jcs.074112
Subject(s) - biology , haematopoiesis , niche , stem cell , stem cell niche , microbiology and biotechnology , evolutionary biology , ecology , progenitor cell
Haematopoietic stem cells (HSCs) regulate the balanced turnover of erythrocytes, platelets and all immune cells by switching between self-renewal, differentiation, quiescence and dormancy ([Trumpp et al., 2010][1]) and, thereby, maintain homeostasis both in the steady state as well as in response to
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