Open AccessRegulation of the Apaf-1–caspase-9 apoptosome
Author(s) -
Shawn B. Bratton,
Guy S. Salvesen
Publication year - 2010
Publication title -
journal of cell science
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.384
H-Index - 278
eISSN - 1477-9137
pISSN - 0021-9533
DOI - 10.1242/jcs.073643
Subject(s) - biology , apoptosome , caspase , genetics , apoptosis , programmed cell death
Apoptosis is probably not the only form of cell death, but it is currently the only form for which the proteins that constitute the death pathway have been characterized at the structural, biochemical and genetic levels in great detail. Apoptosis is an ancient paradigm, going back to the earliest
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