Lipid droplets at a glance
Author(s) -
Yi Guo,
Kimberly R. Cordes,
Robert V. Farese,
Tobias C. Walther
Publication year - 2009
Publication title -
journal of cell science
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.384
H-Index - 278
eISSN - 1477-9137
pISSN - 0021-9533
DOI - 10.1242/jcs.037630
Subject(s) - biology , lipid droplet , perilipin , organelle , endosome , lipid metabolism , microbiology and biotechnology , endoplasmic reticulum , biogenesis , membrane contact site , peroxisome , intracellular , biochemistry , membrane protein , integral membrane protein , adipose tissue , membrane , lipolysis , gene
Lipid droplets (LDs) are the major cellular organelles for the storage of neutral lipids. Excessive lipid storage in LDs is central to the pathogenesis of prevalent metabolic diseases, such as obesity, diabetes and atherosclerosis; LDs are, therefore, crucial in the development of these diseases.
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