Podosomes at a glance | Zendy

Stefan Linder | Zendy; Petra Kopp | Zendy

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Podosomes at a glance

Author(s) -

Stefan Linder,

Petra Kopp

Publication year - 2005

Publication title -

journal of cell science

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.384

H-Index - 278

eISSN - 1477-9137

pISSN - 0021-9533

DOI - 10.1242/jcs.02390

Subject(s) - focal adhesion , podosome , vinculin , paxillin , tensin , extracellular matrix , microbiology and biotechnology , integrin , biology , invadopodia , ptk2 , actin , actin cytoskeleton , cytoskeleton , signal transduction , cell , biochemistry , genetics , pten , mitogen activated protein kinase kinase , protein kinase c , pi3k/akt/mtor pathway , cancer , cancer cell

Cells can contact the extracellular matrix (ECM) through a variety of specialized structures. These cell-matrix contacts contain membrane proteins such as integrins, which bind both matrix components and cellular proteins, thus bridging the substratum and the cytoskeleton (reviewed in [Adams, 2001][

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