Open AccessWASP and SCAR/WAVE proteins: the drivers of actin assembly
Author(s) -
Alice Y. Pollitt,
Robert H. Insall
Publication year - 2009
Publication title -
journal of cell science
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.384
H-Index - 278
eISSN - 1477-9137
pISSN - 0021-9533
DOI - 10.1242/jcs.023879
Subject(s) - wiskott–aldrich syndrome protein , biology , actin , microbiology and biotechnology , actin cytoskeleton , cytoskeleton , dictyostelium discoideum , actin binding protein , gene , genetics , cell
The actin cytoskeleton plays an essential role in numerous aspects of cell biology, such as cell morphology and motility. Actin's role in these processes is tightly regulated, in particular through the Arp2/3 complex ([Goley and Welch, 2006][1]), a major initiator of actin polymerisation that
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