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G-protein-coupled receptors at a glance
Author(s) -
Wesley K. Kroeze,
Douglas J. Sheffler,
Bryan L. Roth
Publication year - 2003
Publication title -
journal of cell science
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.384
H-Index - 278
eISSN - 1477-9137
pISSN - 0021-9533
DOI - 10.1242/jcs.00902
Subject(s) - biology , receptor , computational biology , microbiology and biotechnology , biochemistry
G-protein-coupled receptors (GPCRs) constitute a large and diverse family of proteins whose primary function is to transduce extracellular stimuli into intracellular signals. They are among the largest and most diverse protein families in mammalian genomes. On the basis of homology with rhodopsin,

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