The future of cancer therapy: an interview with Gerard Evan | Zendy

Kristin H. Kain | Zendy

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The future of cancer therapy: an interview with Gerard Evan

Author(s) -

Kristin H. Kain

Publication year - 2008

Publication title -

disease models and mechanisms

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.327

H-Index - 83

eISSN - 1754-8411

pISSN - 1754-8403

DOI - 10.1242/dmm.001396

Subject(s) - cancer therapy , cancer , work (physics) , gerontology , sociology , medicine , cancer research , engineering , mechanical engineering

Will there be a cure for cancer? The heterogeneity of the disease and its regulation by the signaling cascades that are fundamental components for the survival of all cells make this one of the greatest challenges in modern medicine. Gerard Evan’s work helped define the role of transcription factors, such as Myc and p53, in the regulation of cell death pathways and the formation of cancer. Now, many are looking to regulation of these proteins to provide effective, new treatments for cancer.

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