Open AccessThe use of GEM models for experimental cancer therapeutics
Author(s) -
Aarthi Gopinathan,
David A. Tuveson
Publication year - 2008
Publication title -
disease models and mechanisms
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.327
H-Index - 83
eISSN - 1754-8411
pISSN - 1754-8403
DOI - 10.1242/dmm.000570
Subject(s) - cancer , cancer research , medicine , genetically engineered , preclinical testing , in vivo , computational biology , bioinformatics , biology , gene , microbiology and biotechnology , genetics
> GEM models that accurately model human cancer at both the molecular and phenotypic levels are new tools that are available for experimental therapeutic studiesThe proposal of new therapeutic strategies for cancer patients has been greatly facilitated by our deepening knowledge of the molecular
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