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The histone acetyltransferase HBO1 (KAT1) is required for histone H3 lysine 14 acetylation, which is crucial for embryonic development. A new paper in Development reveals that, in the vascular system, HBO1 is required in endothelial cells for sprouting angiogenesis regulation. To hear more about the story, we caught up with first author Zoe Grant and senior authors Professor Anne Voss, Associate Professor Tim Thomas and Leigh Coultas, Business Development Manager, from the Walter and Eliza Hall Institute of Medical Research (WEHI), Australia.

The people behind the papers – Zoe Grant, Tim Thomas, Anne Voss and Leigh Coultas