Advances in live imaging early mouse development: exploring the researcher's interdisciplinary toolkit | Zendy

Matthew J. Stower | Zendy; Shankar Srinivas | Zendy

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Advances in live imaging early mouse development: exploring the researcher's interdisciplinary toolkit

Author(s) -

Matthew J. Stower,

Shankar Srinivas

Publication year - 2021

Publication title -

development

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 3.754

H-Index - 325

eISSN - 1477-9129

pISSN - 0950-1991

DOI - 10.1242/dev.199433

Subject(s) - biology , live cell imaging , embryogenesis , embryo , developmental biology , computational biology , cognitive science , engineering ethics , microbiology and biotechnology , genetics , engineering , psychology , cell

Live imaging is an important part of the developmental biologist's armoury of methods. In the case of the mouse embryo, recent advances in several disciplines including embryo culture, microscopy hardware and computational analysis have all contributed to our ability to probe dynamic events during early development. Together, these advances have provided us with a versatile and powerful ‘toolkit’, enabling us not only to image events during mouse embryogenesis, but also to intervene with them. In this short Spotlight article, we summarise advances and challenges in using live imaging specifically for understanding early mouse embryogenesis.

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