Harnessing brain development to understand brain tumours
Author(s) -
Silvia Marino,
Richard J. Gilbertson
Publication year - 2021
Publication title -
development
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.754
H-Index - 325
eISSN - 1477-9129
pISSN - 0950-1991
DOI - 10.1242/dev.193342
Subject(s) - biology , brain development , pathogenesis , neuroscience , bioinformatics , immunology
Brain tumours are the commonest solid neoplasms in children, accounting for one quarter of all childhood cancers. Our growing knowledge of basic developmental mechanisms has significantly contributed to understanding the pathogenesis of these tumours and is beginning to impact clinical decisions on how children with these diseases are treated.
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