Cell behaviors and dynamics during angiogenesis
Author(s) -
Charles Betz,
Anna Lenard,
HeinzGeorg Belting,
Markus Affolter
Publication year - 2016
Publication title -
development
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.15
H-Index - 36
eISSN - 1477-9129
pISSN - 0950-1991
DOI - 10.1242/dev.135616
Subject(s) - biology , angiogenesis , microbiology and biotechnology , endothelial stem cell , in vivo , cell , sprouting angiogenesis , neovascularization , cancer research , in vitro , genetics
Vascular networks are formed and maintained through a multitude of angiogenic processes, such as sprouting, anastomosis and pruning. Only recently has it become possible to study the behavior of the endothelial cells that contribute to these networks at a single-cell level in vivo This Review summarizes what is known about endothelial cell behavior during developmental angiogenesis, focusing on the morphogenetic changes that these cells undergo.
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