Large-scale live imaging of adult neural stem cells in their endogenous niche | Zendy

Nicolas Dray | Zendy; Sébastien Bedu | Zendy; Nelly Vuillemin | Zendy; Alessandro Alunni | Zendy; Marion Coolen | Zendy; Mónika Krecsmarik | Zendy; Willy Supatto | Zendy; Emmanuel Beaurepaire | Zendy; Laure BallyCuif | Zendy

AI Assistant Blog Pricing

Home ZAIA Blog

Open Access

Large-scale live imaging of adult neural stem cells in their endogenous niche

Author(s) -

Nicolas Dray,

Sébastien Bedu,

Nelly Vuillemin,

Alessandro Alunni,

Marion Coolen,

Mónika Krecsmarik,

Willy Supatto,

Emmanuel Beaurepaire,

Laure BallyCuif

Publication year - 2015

Publication title -

development

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.15

H-Index - 36

eISSN - 1477-9129

pISSN - 0950-1991

DOI - 10.1242/dev.123018

Subject(s) - biology , niche , neural stem cell , stem cell , population , live cell imaging , neuroscience , anatomy , microbiology and biotechnology , ecology , genetics , demography , sociology , cell

Live imaging of adult neural stem cells (aNSCs) in vivo is a technical challenge in the vertebrate brain. Here, we achieve long-term imaging of the adult zebrafish telencephalic neurogenic niche and track a population of >1000 aNSCs over weeks, by taking advantage of fish transparency at near-infrared wavelengths and of intrinsic multiphoton landmarks. This methodology enables us to describe the frequency, distribution and modes of aNSCs divisions across the entire germinal zone of the adult pallium, and to highlight regional differences in these parameters.

The content you want is available to Zendy users.

Already have an account? Click here to sign in.

Having issues? You can contact us here

Accelerating Research