Wingless can bring about a mesoderm-to-ectoderm induction in Drosophila embryos | Zendy

Peter A. Lawrence | Zendy; Paul R. Johnston | Zendy; JeanPaul Vincent | Zendy

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Wingless can bring about a mesoderm-to-ectoderm induction in Drosophila embryos

Author(s) -

Peter A. Lawrence,

Paul R. Johnston,

JeanPaul Vincent

Publication year - 1994

Publication title -

development

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 3.754

H-Index - 325

eISSN - 1477-9129

pISSN - 0950-1991

DOI - 10.1242/dev.120.12.3355

Subject(s) - mesoderm , ectoderm , biology , engrailed , germ layer , gastrulation , fgf and mesoderm formation , embryo , nodal , microbiology and biotechnology , genetics , endoderm , embryogenesis , anatomy , homeobox , embryonic stem cell , gene expression , gene , induced pluripotent stem cell

By means of nuclear transplantations, we make mosaics in which largely wingless- embryos contain patches of wingless+ cells. In these genetic mosaics, using a standard assay for wingless function (the maintenance of engrailed expression), we uncover an induction across germ layers: Wingless made in the mesoderm can sustain engrailed expression in the ectoderm. This result makes clear that Wingless is expressed in the mesoderm until at least one hour after gastrulation and may function in this germ layer in the wild type.

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