Open AccessPresence of basic fibroblast growth factor in the early Xenopus embryo
Author(s) -
Jonathan Slack,
Harry V. Isaacs
Publication year - 1989
Publication title -
development
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.754
H-Index - 325
eISSN - 1477-9129
pISSN - 0950-1991
DOI - 10.1242/dev.105.1.147
Subject(s) - xenopus , biology , mesoderm , embryo , fgf and mesoderm formation , microbiology and biotechnology , salientia , embryogenesis , nodal , inducer , blot , genetics , embryonic stem cell , gene , gastrulation
Mesoderm-inducing activity can be extracted from eggs or whole ovary. It binds to heparin and can be heparin or anti-bFGF but not by anti-TGFbeta. Two be identified by Western blotting and have molecular 19 and 14K. The content in embryos is about 7unitsg-1 7ngml-1) which would be sufficient for it to be acting inducer of ventral mesoderm. Attempts to detect
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