Adult neurogenesis: mechanisms and functional significance | Zendy

Simon M. G. Braun | Zendy; Sebastian Jessberger | Zendy

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Adult neurogenesis: mechanisms and functional significance

Author(s) -

Simon M. G. Braun,

Sebastian Jessberger

Publication year - 2014

Publication title -

development

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 3.754

H-Index - 325

eISSN - 1477-9129

pISSN - 0950-1991

DOI - 10.1242/dev.104596

Subject(s) - neurogenesis , biology , neuroscience , brain function , mammalian brain , disease , function (biology) , microbiology and biotechnology , pathology , medicine

New neurons are generated throughout life in distinct regions of the mammalian brain. This process, called adult neurogenesis, has been implicated in physiological brain function, and failing or altered neurogenesis has been associated with a number of neuropsychiatric diseases. Here, we provide an overview of the mechanisms governing the neurogenic process in the adult brain and describe how new neurons may contribute to brain function in health and disease.

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