Open AccessCycling cytoplasmic factors that promote mitosis in the cultured 2-cell mouse embryo
Author(s) -
H. P. M. Pratt,
A.L. Muggleton-Harris
Publication year - 1988
Publication title -
development
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.754
H-Index - 325
eISSN - 1477-9129
pISSN - 0950-1991
DOI - 10.1242/dev.104.1.115
Subject(s) - biology , cytoplasm , embryo , mitosis , microbiology and biotechnology , cleavage (geology) , in vitro , cell cycle , cell , genetics , paleontology , fracture (geology)
A cytoplasmic component(s), previously shown to rescue the ‘blocked’ 2-cell mouse embryo in vitro, has been demonstrated to peak in activity during the transition between G2 and M phase and decline thereafter. The possible significance of this component(s) in the regulation of cleavage of the cultured mouse embryo is discussed.
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