Skeletal stem cells | Zendy

Paolo Bianco | Zendy; Pamela Gehron Robey | Zendy

AI Assistant Blog Pricing

Home ZAIA Blog

Open Access

Skeletal stem cells

Author(s) -

Paolo Bianco,

Pamela Gehron Robey

Publication year - 2015

Publication title -

development

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.15

H-Index - 36

eISSN - 1477-9129

pISSN - 0950-1991

DOI - 10.1242/dev.102210

Subject(s) - biology , haematopoiesis , bone marrow , stem cell , context (archaeology) , microbiology and biotechnology , cartilage , embryonic stem cell , immunology , anatomy , genetics , gene , paleontology

Skeletal stem cells (SSCs) reside in the postnatal bone marrow and give rise to cartilage, bone, hematopoiesis-supportive stroma and marrow adipocytes in defined in vivo assays. These lineages emerge in a specific sequence during embryonic development and post natal growth, and together comprise a continuous anatomical system, the bone-bone marrow organ. SSCs conjoin skeletal and hematopoietic physiology, and are a tool for understanding and ameliorating skeletal and hematopoietic disorders. Here and in the accompanying poster, we concisely discuss the biology of SSCs in the context of the development and postnatal physiology of skeletal lineages, to which their use in medicine must remain anchored.

The content you want is available to Zendy users.

Already have an account? Click here to sign in.

Having issues? You can contact us here

Accelerating Research