Branching morphogenesis and kidney disease | Zendy

Mita M. Shah | Zendy; Rosemary V. Sampogna | Zendy; Hiroyuki Sakurai | Zendy; Kevin T. Bush | Zendy; Sanjay K. Nigám | Zendy

AI Assistant Blog Pricing

Home ZAIA Blog

Open Access

Branching morphogenesis and kidney disease

Author(s) -

Mita M. Shah,

Rosemary V. Sampogna,

Hiroyuki Sakurai,

Kevin T. Bush,

Sanjay K. Nigám

Publication year - 2004

Publication title -

development

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 3.754

H-Index - 325

eISSN - 1477-9129

pISSN - 0950-1991

DOI - 10.1242/dev.01089

Subject(s) - biology , morphogenesis , kidney development , kidney disease , kidney , broad spectrum , disease , evolutionary biology , pathology , genetics , gene , endocrinology , medicine , chemistry , embryonic stem cell , combinatorial chemistry

Branching morphogenesis in the kidney is a tightly regulated, complex process and its disruption potentially can lead to a broad spectrum of diseases, ranging from rare hereditary syndromes to common conditions such as hypertension and chronic kidney failure. This review synthesizes data on branching during kidney development derived from in vitro and in vivo rodent studies and to apply them to human diseases. It discusses how the broad organization of molecular interactions during kidney development might provide a mechanistic framework for understanding disorders related to aberrant branching.

The content you want is available to Zendy users.

Already have an account? Click here to sign in.

Having issues? You can contact us here

Accelerating Research