Open AccessThe matrix in focus: new directions in extracellular matrix research from the 2021 ASMB hybrid meeting
Author(s) -
Bryan A. Nerger,
Tia M. Jones,
Keron W. J. Rose,
Anna Barqué,
Justin S. Weinbaum,
Ryan J. Petrie,
Joan Chang,
Davy Vanhoutte,
Kendra LaDuca,
Dirk Hubmacher,
Alexandra Naba
Publication year - 2022
Publication title -
biology open
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.936
H-Index - 41
ISSN - 2046-6390
DOI - 10.1242/bio.059156
Subject(s) - extracellular matrix , modalities , biology , engineering ethics , computational biology , cognitive science , computer science , microbiology and biotechnology , data science , engineering , sociology , psychology , social science
The extracellular matrix (ECM) is a complex assembly of macromolecules that provides both architectural support and molecular signals to cells and modulate their behaviors. Originally considered a passive mechanical structure, decades of research have since demonstrated how the ECM dynamically regulates a diverse set of cellular processes in development, homeostasis, and disease progression. In September 2021, the American Society for Matrix Biology (ASMB) organized a hybrid scientific meeting, integrating in-person and virtual formats, to discuss the latest developments in ECM research. Here, we highlight exciting scientific advances that emerged from the meeting including (1) the use of model systems for fundamental and translation ECM research, (2) ECM-targeting approaches as therapeutic modalities, (3) cell-ECM interactions, and (4) the ECM as a critical component of tissue engineering strategies. In addition, we discuss how the ASMB incorporated mentoring, career development, and diversity, equity, and inclusion initiatives in both virtual and in-person events. Finally, we reflect on the hybrid scientific conference format and how it will help the ASMB accomplish its mission moving forward.