Does Intraoperative Ketamine Attenuate Inflammatory Reactivity Following Surgery? A Systematic Review and Meta-Analysis
Author(s) -
Ola Dale,
Andrew A. Somogyi,
Yibai Li,
Thomas Sullivan,
Yehuda Shavit
Publication year - 2012
Publication title -
anesthesia and analgesia
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.404
H-Index - 201
eISSN - 1526-7598
pISSN - 0003-2999
DOI - 10.1213/ane.0b013e3182662e30
Subject(s) - medicine , ketamine , perioperative , meta analysis , randomized controlled trial , anesthesia , cochrane library , premedication , anesthetic , surgery
Reports regarding the ability of the anesthetic drug ketamine to attenuate the inflammatory response to surgery are conflicting. In this systematic review we examined the effect of perioperative ketamine administration on postoperative inflammation as assessed by concentrations of the biomarker interleukin-6 (IL-6).
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