Open AccessBinding Site and Affinity Prediction of General Anesthetics to Protein Targets Using Docking
Author(s) -
Renyu Liu,
Jose Manuel PerezAguilar,
David Liang,
Jeffery G. Saven
Publication year - 2012
Publication title -
anesthesia and analgesia
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.404
H-Index - 201
eISSN - 1526-7598
pISSN - 0003-2999
DOI - 10.1213/ane.0b013e31824c4def
Subject(s) - docking (animal) , isothermal titration calorimetry , anesthetic , autodock , binding site , binding constant , chemistry , computational chemistry , biochemistry , medicine , nursing , psychiatry , in silico , gene
The protein targets for general anesthetics remain unclear. A tool to predict anesthetic binding for potential binding targets is needed. In this study, we explored whether a computational method, AutoDock, could serve as such a tool.
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