Open AccessFresh and Stored Red Blood Cell Transfusion Equivalently Induce Subclinical Pulmonary Gas Exchange Deficit in Normal Humans
Author(s) -
Richard B. Weiskopf,
John Feiner,
Pearl Toy,
Jenifer Twiford,
David Shimabukuro,
Jeremy A. Lieberman,
Mark R. Looney,
Clifford A. Lowell,
Michael A. Gropper
Publication year - 2012
Publication title -
anesthesia and analgesia/anesthesia and analgesia
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.404
H-Index - 201
eISSN - 1526-7598
pISSN - 0003-2999
DOI - 10.1213/ane.0b013e318241fcd5
Subject(s) - medicine , anesthesia , volunteer , packed red blood cells , blood transfusion , red blood cell , subclinical infection , lung , surgery , immunology , agronomy , biology
Transfusion can cause severe acute lung injury, although most transfusions do not seem to induce complications. We tested the hypothesis that transfusion can cause mild pulmonary dysfunction that has not been noticed clinically and is not sufficiently severe to fit the definition of transfusion-related acute lung injury.