The Effects of Isoflurane and Desflurane on Cognitive Function in Humans | Zendy

Bin Zhang | Zendy; Ming Tian | Zendy; Zhen Yu | Zendy; Yun Yue | Zendy; Janet C. Sherman | Zendy; Hui Zheng | Zendy; Shuren Li | Zendy; Rudolph E. Tanzi | Zendy; Edward R. Marcantonio | Zendy; Zhongcong Xie | Zendy

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The Effects of Isoflurane and Desflurane on Cognitive Function in Humans

Author(s) -

Bin Zhang,

Ming Tian,

Zhen Yu,

Yun Yue,

Janet C. Sherman,

Hui Zheng,

Shuren Li,

Rudolph E. Tanzi,

Edward R. Marcantonio,

Zhongcong Xie

Publication year - 2011

Publication title -

anesthesia and analgesia

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.404

H-Index - 201

eISSN - 1526-7598

pISSN - 0003-2999

DOI - 10.1213/ane.0b013e31823b2602

Subject(s) - desflurane , isoflurane , medicine , anesthesia , postoperative cognitive dysfunction , anesthetic , cognition , psychiatry

The etiology of postoperative cognitive decline (POCD) remains to be determined. Anesthetic isoflurane, but not desflurane, may induce neurotoxicity. However, the functional consequences of these effects have not been assessed. We therefore performed a pilot study to determine the effects of isoflurane and desflurane on cognitive function in humans.

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