Open AccessIsoflurane Anesthesia Does Not Satisfy the Homeostatic Need for Rapid Eye Movement Sleep
Author(s) -
George A. Mashour,
William J. Lipinski,
Lisa Matlen,
Amanda J. Walker,
Ashley M. Turner,
Walter Schoen,
UnCheol Lee,
Gina R. Poe
Publication year - 2010
Publication title -
anesthesia and analgesia/anesthesia and analgesia
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.404
H-Index - 201
eISSN - 1526-7598
pISSN - 0003-2999
DOI - 10.1213/ane.0b013e3181d3e861
Subject(s) - isoflurane , anesthesia , medicine , non rapid eye movement sleep , sleep deprivation , sleep (system call) , rapid eye movement sleep , propofol , hippocampal formation , eye movement , circadian rhythm , ophthalmology , computer science , operating system
Sleep and general anesthesia are distinct states of consciousness that share many traits. Prior studies suggest that propofol anesthesia facilitates recovery from rapid eye movement (REM) and non-REM (NREM) sleep deprivation, but the effects of inhaled anesthetics have not yet been studied. We tested the hypothesis that isoflurane anesthesia would also facilitate recovery from REM sleep deprivation.